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Key Issues

Increasing Investment Needed to Develop a New Drug
A tremendous investment in human capital and technology is required to develop new medicines. Read a report that highlights the evolution of the pharmaceutical research and development process and identifies that increasing investment is required to get new drugs to the clinic.

Innovation at a Crossroads
Pharmaceutical discovery is entering a new era. Our new understanding of the genome and powerful scientific research tools are opening new doors to discovery of breakthrough medicines. At the same time, researchers are tackling more complex diseases and facing a more intensive regulatory and policy environment. See what the experts are saying about this crossroads of innovation.

Government Initiatives
U.S. public health officials increasingly are recognizing the unprecedented promise of – and challenges to – discovery of new medicines. Several agencies have launched new initiatives to overcome these challenges and realize the promise of pharmaceutical innovation.

Public - Private Partnerships
Increasingly among research and academic institutions, pharmaceutical and biotechnology companies, and state and local governments, steps are being taken to improve the landscape for innovation. See what partnerships between the public and private sectors are providing opportunities not previously realized that foster innovative approaches to pharmaceutical discovery and development.

Incremental Innovation
Many people see incremental changes in medicines simply as “me-too” drugs. In fact, having multiple choices of medicines within a class offers many benefits to patients, doctors, and society. Learn more about the role of incremental innovation.

Preserving Incentives for Innovation
In an era of new scientific and public policy challenges, preserving a climate that supports innovation is more important than ever. Read how policymakers can preserve the incentives that drive innovation.